Status:
COMPLETED
Image and Model Based Analysis of Lung Disease
Lead Sponsor:
Eric A. Hoffman
Collaborating Sponsors:
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Pulmonary Disease, Chronic Obstructive
Eligibility:
All Genders
20-89 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this research study is to develop CT scanning and image analysis techniques to help define and measure several key properties of the pulmonary system that cannot be obtained by other te...
Detailed Description
Specifically, the investigators are interested in understanding the difference between the normal aging process and the events that lead to emphysema. Additionally, the investigators are interested in...
Eligibility Criteria
Inclusion
- Non smokers, age 20-29, 40-49, 60-69, 80-89, cannot have smoked more than 20 cigarettes in their lifetime
- Smokers, age 20-29, 40-49, 60-69, 80-89, currently smoking a minimum of 1 pack (20 cigarettes) per day, normal smokers and mild to moderate Chronic Obstructive Pulmonary Disease (COPD)
Exclusion
- Allergies - no allergies to shellfish, eggs, iodine
- Medications - no medications (except for birth control) for in the 'normal' category
- No asthma - as self reported
- BMI (Body Mass Index) - must not exceed 32 or 100kg of weight
- No other radiology studies in the last 12 months
- No metal in lung field - no metal from larynx to stomach
- No known heart disease
- No known kidney disease or diabetes
- Must not be pregnant - subjects of childbearing potential with be given a urine pregnancy test
Key Trial Info
Start Date :
September 30 1997
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 5 2015
Estimated Enrollment :
341 Patients enrolled
Trial Details
Trial ID
NCT03764163
Start Date
September 30 1997
End Date
June 5 2015
Last Update
January 22 2019
Active Locations (1)
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1
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242