Status:

COMPLETED

Modification of Goal-directed and Habitual Behavior in Addiction

Lead Sponsor:

Central Institute of Mental Health, Mannheim

Conditions:

Tobacco Use Disorder

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This study aims to examine the modification of the hypothesized imbalance between goal-directed and habitual behavior and its neural correlates in smokers. Two interventions will be used as add-on tra...

Detailed Description

In this study, the investigators aim to assess the imbalance between goal-directed and habitual behavior, its neural basis and how it can be differentially modified in treatment-seeking smokers, using...

Eligibility Criteria

Inclusion

  • severe tobacco use disorder (TUD) according to DSM-5
  • sufficient ability to communicate with investigators and answer questions in both written and verbal format
  • ability to provide fully informed consent and to use self-rating scales

Exclusion

  • severe internal, neurological, and/or psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for mild depression, i.e. F32.0, adjustment disorder and specific phobias) in the last 12 months
  • history of brain injury
  • severe physical diseases
  • common exclusion criteria for MRI (e.g. metal, claustrophobia)
  • positive drug screening (opioids, benzodiazepines, barbiturates, cocaine, amphetamines)
  • psychotropic medication within the last 14 days
  • pregnancy

Key Trial Info

Start Date :

January 7 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 23 2023

Estimated Enrollment :

75 Patients enrolled

Trial Details

Trial ID

NCT03764969

Start Date

January 7 2020

End Date

June 23 2023

Last Update

October 5 2023

Active Locations (1)

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Klinik für Abhängiges Verhalten, Zentralinstitut für Seelische Gesundheit

Mannheim, Baden-Wurttemberg, Germany, 68159