Status:

UNKNOWN

Tranexamic Acid vs Fractional CO2 Laser in Post-acne Hyperpigmentation

Lead Sponsor:

Cairo University

Conditions:

Post Inflammatory Hyperpigmentation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

comparing between the effect of intradermal injection of TXA and low power low density fractional CO2 lasers on post acne hyperpigmentation

Detailed Description

Randomized controlled split-face study. One side of the face will be assigned to TXA intradermal microinjection using Kapron 500mg/5ml ampoules (Amoun Pharmaceutical Company), the dose of 1 ml syringe...

Eligibility Criteria

Inclusion

  • Egyptians of both sexes.
  • Age \> 18.
  • Patients who can avoid sun exposure one week after sessions.
  • Patients who stopped taking systemic isotretinoin for more than six months.

Exclusion

  • Pregnancy and lactation.
  • Concomitant use of anticoagulants.
  • Bleeding disorders.
  • Personal or family history of DVT or thromboembolic events.
  • Scarring and keloid tendency.
  • Active skin infection, active HSV.
  • History of photosensitivity or photosensitizing medication.
  • Occupational sun exposure.

Key Trial Info

Start Date :

December 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2019

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT03765021

Start Date

December 1 2018

End Date

July 1 2019

Last Update

December 5 2018

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