Status:

COMPLETED

A Study Comparing User Experience of Different Delivery Devices for Glucagon

Lead Sponsor:

Eli Lilly and Company

Conditions:

Healthy

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

The purpose of the study is to learn more about different devices for delivering glucagon during simulations of severe hypoglycemic (low blood sugar) emergencies. The study will be carried out using m...

Eligibility Criteria

Inclusion

  • All participants (Trained Users, Participants with Diabetes \[PWDs\] and Untrained Users):
  • Are able to understand the purpose and procedure of the study and to give written informed consent to show willingness to participate in the study
  • Trained Users only:
  • Are participants who are not diagnosed with Type 1 Diabetes Mellitus (T1DM) or Type 2 Diabetes Mellitus (T2DM)
  • Are close friends/relatives of a patient with T1DM or T2DM on insulin
  • Have not previously administered any rescue medications (e.g. epinephrine, glucagon, narcan or seizure medications)
  • Untrained Users only:
  • Have not been diagnosed with T1DM or T2DM, and are not a Trained User of a person with T1DM or T2DM
  • Have not previously administered any rescue medications (e.g. epinephrine, glucagon, narcan or seizure medications)

Exclusion

  • All participants (Trained Users, PWDs and Untrained Users):
  • In the opinion of the investigator or sponsor, are unsuitable for inclusion in the study
  • Trained Users and Untrained Users only (i.e. the participants involved in the simulations):
  • Are currently enrolled in a clinical study involving any type of medical research judged not to be scientifically or medically compatible with this study
  • Are judged by the investigator as being likely to have difficulty performing the administration due to physical, cognitive and/or severe psychiatric disorder
  • Are judged by the investigator as being trained or experienced in performing rescue drug administration
  • Are judged by the investigator as being trained or experienced in performing high-fidelity simulations of drug administration
  • Have received formal training in a medical field, and/or worked in this field within the prior 5 years; or otherwise are judged by the investigator as being trained or experienced as a first responder

Key Trial Info

Start Date :

November 19 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 3 2019

Estimated Enrollment :

99 Patients enrolled

Trial Details

Trial ID

NCT03765502

Start Date

November 19 2018

End Date

January 3 2019

Last Update

March 20 2020

Active Locations (1)

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High Point Clinical Trials Center

High Point, North Carolina, United States, 27265