Status:
COMPLETED
Postoperative Aspirin and Ankle Fracture Healing
Lead Sponsor:
University of Alabama at Birmingham
Conditions:
Ankle Fractures
Eligibility:
All Genders
18-110 years
Phase:
EARLY_PHASE1
Brief Summary
This study aims to identify if postoperative aspirin use leads to a delay in fracture healing. NSAIDs have long been avoided in the management of fractures, due to the belief that they may impair frac...
Detailed Description
Despite any new clinical research on aspirin's effects on fracture healing, it is now being used more commonly in the setting of fracture due to its effectiveness as a means of VTE prophylaxis followi...
Eligibility Criteria
Inclusion
- Over 18 years of age
- healthy enough for orthopedic surgery
- slated to undergo surgical repair of ankle fracture at UAB
- able to give consent All ankle fractures (lateral malleolus, medial malleolus, bimalleolar, trimalleolar, and proximal fibula) will be included in this study.
Exclusion
- Under 18 years of age
- inability to give consent
- Pilon fractures
- Multiple traumatic fractures
- Known history of aspirin allergy
- History of severe reaction to aspirin
- History of bleeding disorder
- Other clear contraindication to being prescribed aspirin
- Taking blood-thinning medications (heparin, apixaban, etc)
- Taking aspirin prior to the start of the study
Key Trial Info
Start Date :
June 12 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 26 2019
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT03765619
Start Date
June 12 2019
End Date
November 26 2019
Last Update
January 13 2025
Active Locations (1)
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1
UAB Highland Hospital
Birmingham, Alabama, United States, 35205