Status:
COMPLETED
Role of Dietary Protein Intake in Elderly Adults
Lead Sponsor:
University of Arkansas
Conditions:
Protein Overload
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The investigators examined the effects of dietary protein intake in a mixed meal at two levels of protein amount on whole body protein metabolisms in older adults.
Detailed Description
The investigators determined the total anabolic response to an amount of protein intake commonly eaten with dinner (70g) as compared with the amount required to maximally stimulate muscle protein synt...
Eligibility Criteria
Inclusion
- Men and women, ages \> 60 years
Exclusion
- History of diabetes
- History of malignancy in the 6 months prior to enrollment
- History of gastrointestinal bypass surgery (Lapband, etc)
- History of a chronic inflammatory condition or disease (Lupus, HIV/AIDS, etc)
- Pregnant females
- Subjects who do not or will not eat animal proteins
- Subjects who cannot refrain from consuming protein or amino acid supplements during their participation in this study
- Subjects who report regular resistance exercise (more than once per week)
- Hemoglobin less than 9.5 mg/dL at the screening visit
- Platelets less than 150,000 at the screening visit
- Subjects who are not willing or able to suspend aspirin for several days prior to their muscle biopsies
- Subjects who have been prescribed a blood-thinning medication (Coumadin, lovenox, heparin, Plavix, etc.)
- Concomitant use of corticosteroids (ingestion, injection or transdermal)
- Any other disease or condition that would place the subject at increased risk of harm if they were to participate, at the discretion of the study physician
Key Trial Info
Start Date :
August 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2016
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03765710
Start Date
August 1 2015
End Date
September 1 2016
Last Update
April 26 2023
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