Status:
UNKNOWN
Study of Postoperative Cognitive Decline in Aged Patients
Lead Sponsor:
Jia-feng Wang
Conditions:
Cognitive Decline
Eligibility:
All Genders
65-85 years
Brief Summary
postoperative cognitive decline is a common and deleterious complication in aged patients.The link between inflammation and postoperative cognitive decline has also been reported.However,the link betw...
Eligibility Criteria
Inclusion
- patients who are more than 65 years old
- patients who undergo orthopedic surgery(trauma ,especially fracture of lower limb)
- patients with ASA physical status I-III
- patients who have a consent
Exclusion
- patients who are more than 85 years old
- patients with ASA physical status \>III
- patients who have neurological disorders, stroke or other affective central nervous system diseases
- patients who have a history of serious psychiatric illness
- patients with long-term use of psychoactive substances
- patients who undergo multiple trauma and the presence of head injury
Key Trial Info
Start Date :
May 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2021
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03765840
Start Date
May 1 2018
End Date
May 1 2021
Last Update
December 5 2018
Active Locations (1)
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1
Deartment of anesthesiology,changhai hospital
Shanghai, Shanghai Municipality, China, 200433