Status:
ACTIVE_NOT_RECRUITING
Concordance Between FFR and iFR for the Assessment of Intermediate Lesions in the Left Main Coronary Artery. A Prospective Validation of a Default Value for iFR
Lead Sponsor:
Fundación EPIC
Conditions:
Coronary Artery Disease
Left Main Coronary Artery Stenosis
Eligibility:
All Genders
18+ years
Brief Summary
The assessment of Left Main Coronary Artery (LMCA) lesions by means of coronary angiography renders serious limitations. Studies with a limited number of patients have shown that a value of FFR (Frac...
Detailed Description
The assessment of Left Main Coronary Artery (LMCA) lesions by means of coronary angiography renders serious limitations. In the case of intermediate stenoses (25-60%), invasive imaging tests, intravas...
Eligibility Criteria
Inclusion
- Patients with intermediate lesion in the LMCA (25-60% angiographic stenosis) by visual estimation) in which the realization of a study with guide of pressure for the determination of the iFR.
- Patients aged ≥18 years.
- Patients able of giving informed consent.
Exclusion
- Patients with indication for coronary surgery regardless of the significance of the LMCA lesion.
- Patients with a LMCA lesion presenting with ulceration, dissection or thrombus.
- Patients with previous arterial or venous graft lesion functioning in the territory irrigated by the LMCA (LMCA protected).
- Patients with ACS (Acute Coronary Syndrome) with a potentially guilty lesion in the LMCA.
- Patients unable to obtain informed consent.
- Patients with known terminal illness that conditions a life expectancy less than 1 year.
- Patients with hemodynamic instability with Killip III or IV class.
Key Trial Info
Start Date :
February 19 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2026
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03767621
Start Date
February 19 2019
End Date
November 30 2026
Last Update
March 5 2025
Active Locations (38)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital Universitari Mutua de Terrassa
Terrassa, Barcelona, Spain, 08221
2
Hospital General Universitario de Santa Lucia de Cartagena
Cartagena, Murcia, Spain, 30202
3
Hospital Clinico Universitario Virgen de La Arrixaca
El Palmar, Murcia, Spain, 30120
4
Hospital General Universitario de Castellón
Castellon, Valencia, Spain, 12004