Status:
TERMINATED
Comparison of Magnetic Resonance Coronary Angiography (MRCA) With Coronary Computed Tomography Angiography (CTA)
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Canon Medical Systems, USA
Conditions:
Magnetic Resonance Angiography
Eligibility:
All Genders
18+ years
Brief Summary
Magnetic resonance coronary angiography (MRCA) has its advantage in its ability to assess the coronary artery morphology without radiation or contrast media. The clinical application of MRCA is still ...
Detailed Description
Background: Diagnosis of significant stenosis of the coronary artery and managing the ischemia is important to prevent cardiac events. Coronary CT angiography (CTA) is one of the current gold standar...
Eligibility Criteria
Inclusion
- Participants who underwent clinical coronary CTA within 6 months and allow the study to use the image.
- Willing to sign a consent.
- Overall health status is rated as good/healthy other than suspected coronary artery disease
- Weight is \<300 pounds
- Not claustrophobic
- Age: 18 or older
- No clear contraindication against the sublingual nitro administration
Exclusion
- Previous history of bypass surgery or percutaneous coronary intervention (PCI)
- Metal fragments in the eyes, brain, or spinal cord
- Internal electrical devices, such as a cochlear implant, spinal cord stimulator, pacemaker, or defibrillator
- Pregnancy
- Claustrophobia
- Unstable angina pectoris patients
- Taking phosphodiesterase V inhibitors (If the participant is taking this medication for erectile dysfunction and allowed to stop it for 72 hours before the MRI, the participant can be included in this study.)
- Contraindication to use sublingual nitro administration, such as occlusive glaucoma, known allergy or severe intolerance, critical aortic stenosis. Blood pressure is not included in the exclusion criteria, but when the SBP\<110 mmHg just before the cardiac MRI, the participant will not be administered the sublingual nitro.
Key Trial Info
Start Date :
September 3 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2025
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03768999
Start Date
September 3 2019
End Date
July 31 2025
Last Update
August 12 2025
Active Locations (1)
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1
Division of Cardiology, Johns Hopkins University School of Medicine
Baltimore, Maryland, United States, 21287