Status:
COMPLETED
The Influence of Citric Acid Bone Surface Etching and Bone Defect Fill on GCF BMP-2 Release Profile
Lead Sponsor:
Ain Shams University
Conditions:
Intrabony Periodontal Defect
Eligibility:
All Genders
20-60 years
Phase:
PHASE4
Brief Summary
This study evaluates the effect of citric acid on bone surface of infrabony defects when used for 30 seconds at ph 1 and 50% concentration before the application of bovine derived xenograft to fill th...
Detailed Description
Citric acid have been widely used to treat root surfaces of periodontally affected teeth in order to render it biologically suitable for fibroblast reattachment. however, systematic reviews showed no ...
Eligibility Criteria
Inclusion
- Both genders aged between 32-60 years.
- Selected patient with a single site of:
- Two walled or three walled infra-bony defect.
- The bone defect should be at least 3 mm in depth from the crest of the alveolar bone to the base of the defect.
- Pocket depth of more than or equal to 5 mm.
- Clinical attachment loss equal or more than 3mm
- Patients ready to comply with oral hygiene measures.
Exclusion
- Any systemic disease that contra-indicates periodontal surgery or may affect healing.
- Smokers
- Pregnant females
- Drug abusers
Key Trial Info
Start Date :
January 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2018
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03769402
Start Date
January 1 2016
End Date
November 1 2018
Last Update
December 7 2018
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