Status:
COMPLETED
Autologous Platelet-rich Plasma for Clomiphene Citrate-induced Thin Endometrium
Lead Sponsor:
Benha University
Conditions:
Infertility, Female, Associated With Anovulation
Eligibility:
FEMALE
18-35 years
Phase:
PHASE2
PHASE3
Brief Summary
This is a prospective self-controlled clinical study. Women with clomiphene Citrate failure with thin endometrium less than 7 millimeters for at least 3 cycles will be selected (N = 30). Patients will...
Detailed Description
This is a pilot prospective self-controlled clinical trial. Women with Clomiphene Citrate failure with documented thin endometrium less than 7 millimeters for at least 3 stimulation cycles will be cho...
Eligibility Criteria
Inclusion
- Women with clomiphene citrate failure (defined as at least previous 3 ovulatory cycles with clomiphene citrate, with no pregnancy),
- persistently thin endometrium (less than 7 millimeters in at least 3 cycles).
- normal baseline Follicle Stimulating Hormone, Luteinizing Hormone, and free testosterone levels, patent tubes by hysterosalpingography, and satisfactory male semen analysis
Exclusion
- previous ovarian surgery;
- endocrine disorders ;
- pelvic pathologies;
- chronic hepatic, cardiovascular, or renal disease;
- other factors of infertility and
- use of gonadotropins or hormonal contraception through the latest 6 months.
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03770026
Start Date
January 1 2018
End Date
January 1 2020
Last Update
April 29 2020
Active Locations (1)
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1
Banha Faculty Hospital
Banhā, Alkalubia, Egypt, 13511