Status:

COMPLETED

Study of the Effect of Prehabilitation on Markers of Sarcopenia in Patients Undergoing Pancreatoduodenectomy for Malignant Disease

Lead Sponsor:

Manchester University NHS Foundation Trust

Conditions:

Pancreatic Ductal Adenocarcinoma

Eligibility:

All Genders

16-100 years

Brief Summary

The aim of this study is to assess whether prehabilitation supervised by an appropriate multimodality team improves indices of sarcopenia in patients scheduled to undergo pancreatoduodenectomy.

Detailed Description

Cachexia is a hallmark feature of pancreatic cancer. Patients with features of cachexia have worse clinical outcomes. This includes a reduction in quality of life, reduced tolerance of therapy and a p...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • Patients treated by pancreatic resection
  • Surgery for malignancy
  • Patients aged over 16
  • CT scans available for assessment
  • Exclusion criteria
  • Patients scheduled for fast-track pancreatic resection as part of the jaundice pathway
  • Aged under 16
  • Patients not undergoing pancreatic resection

Exclusion

    Key Trial Info

    Start Date :

    October 4 2018

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2019

    Estimated Enrollment :

    113 Patients enrolled

    Trial Details

    Trial ID

    NCT03770117

    Start Date

    October 4 2018

    End Date

    July 1 2019

    Last Update

    January 19 2021

    Active Locations (1)

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    Manchester University NHS Foundation Trust

    Manchester, Gtr Manchester, United Kingdom, M13 9WL