Status:

COMPLETED

Investigating the Sensory Attributes of Selenium-fortified Biscuits and Their Effects on Selenium-status

Lead Sponsor:

Newcastle University

Collaborating Sponsors:

Fera Science Ltd.

Conditions:

Selenium Status

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This intervention study will investigate the relationship between consumption of selenium-fortified biscuits fortified with selenium-enriched yeast (approximately 60mcg of selenium per day for 14 days...

Detailed Description

There are different forms of selenium supplementation which may be used to improve selenium-status, one being selenium-enriched yeast. Selenium is an essential micronutrient consumed through food, ho...

Eligibility Criteria

Inclusion

  • Adult human volunteers, 18 years of age or older.
  • Generally healthy, meaning that if health issues such as hypertension, diabetes, arthritis etc. are present, they are well controlled by appropriate treatments.
  • Upon tasting the screening biscuit, are confident they would be able to eat the specified amount every day for 14 consecutive days.
  • No taste or smell disorders.
  • No difficulties with chewing and/or swallowing.
  • No intolerances and/or allergies to any of the test foods.
  • No impairments which may prevent mental understanding of the trial, or informed consent from being given.
  • No disorders/medication that would make blood sampling dangerous to their health.
  • Plasma selenium not lower than 28 µg/L or higher than 400 µg/L on analysis
  • Participants need to be able to visit Newcastle University for the scheduled visits.
  • Participants must have been living in the UK for at least 6 months.

Exclusion

  • Do not meet all requirements in the inclusion criteria.

Key Trial Info

Start Date :

December 3 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 15 2020

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT03770676

Start Date

December 3 2018

End Date

March 15 2020

Last Update

January 18 2022

Active Locations (1)

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NU-Food

Newcastle upon Tyne, Tyne & Wear, United Kingdom, NE1 7RU