Status:

UNKNOWN

Evaluating Structural and Functional Changes of Brain by fMRI and DTI in Patients With Intracranial Germ Cell Tumors

Lead Sponsor:

Beijing Neurosurgical Institute

Conditions:

Intracranial Germ Cell Tumor

Eligibility:

All Genders

3+ years

Brief Summary

BOLD-fMRI and DTI scans are performed to patients with germ cell tumors in the basal ganglia before and after treatments. The changes of the MRI and muscle strength of patients during treatments are e...

Detailed Description

Primary intracranial germ cell tumors are a specific entity of brain tumors with a variety of histological types and different degrees of malignancy. Intracranial GCTs make up 11.2% - 15.3% of primary...

Eligibility Criteria

Inclusion

  • age ≥3 years;
  • no history of brain radiotherapy;
  • no other known cause of movement and cognitive impairment;
  • no contraindications to the magnetic resonance imaging (MRI) scan;

Exclusion

  • patients can not tolerate MR scan;
  • head motion is greater than 3 mm during functional MRI scanning.

Key Trial Info

Start Date :

June 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03771625

Start Date

June 1 2019

End Date

November 1 2021

Last Update

July 29 2019

Active Locations (1)

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Beijing Tiantan Hospital

Beijing, China, 100071