Status:

COMPLETED

Individual Variability of Appetite Responses to a Standardised Meal

Lead Sponsor:

Loughborough University

Collaborating Sponsors:

Teesside University

Conditions:

Appetitive Behavior

Obesity

Eligibility:

MALE

18-50 years

Phase:

NA

Brief Summary

The aim of this study is to examine the interindividual variability of subjective and hormonal appetite responses to a standardised meal in healthy men and explore any moderating influence of the fat ...

Detailed Description

Meal ingestion initiates a series of co-ordinated subjective and hormonal appetite responses. However, it is not known whether interindividual variability in appetite exists in response to a standardi...

Eligibility Criteria

Inclusion

  • Homozygous minor allele (AA) or major allele (TT) FTO rs9939609 genotype;
  • Non-smoker;
  • Weight stable for the previous 3 months.

Exclusion

  • Heterozygous FTO rs9939609 genotype (i.e., AT);
  • Any medical conditions (e.g., diabetes, coagulation or bleeding disorders);
  • Taking any medication that might influence appetite, fat metabolism or blood glucose;
  • Dieting or restrained eating behaviours;
  • Any food allergies.

Key Trial Info

Start Date :

January 11 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2018

Estimated Enrollment :

18 Patients enrolled

Trial Details

Trial ID

NCT03771690

Start Date

January 11 2018

End Date

May 1 2018

Last Update

December 11 2018

Active Locations (1)

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Loughborough University

Loughborough, Leicestershire, United Kingdom, LE11 3TU