Status:

UNKNOWN

Predictive Value of Infarction Volume on Hemorrhagic Transformation in Ischemic Stroke/TIA With Non-valve Atrial Fibrillation(NVAF) Patients Using Rivaroxaban

Lead Sponsor:

Second Affiliated Hospital, School of Medicine, Zhejiang University

Collaborating Sponsors:

Bayer

Taizhou Hospital

Conditions:

Cerebrovascular Stroke

Intracranial Hemorrhages

Eligibility:

All Genders

18+ years

Brief Summary

This study was aimed at patients with newly diagnosed stroke / TIA associated with nonvalvular atrial fibrillation. We will observe the effect of early using rivaroxaban anticoagulation on hemorrhagic...

Eligibility Criteria

Inclusion

  • Male or female, age≥18;
  • Were newly diagnosed asischemic stroke/TIA concomitant NVAF;
  • Prescribedand accept Rivaroxaban;
  • Sign thewritten informed consent.

Exclusion

  • Renal impairment (CrCl\<15 ml/min) or severe hepatic impairment.
  • Significant hemorrhagic transformation (parenchymal hematoma type I or type II by the ECASS definition).
  • Stroke or TIA caused by large artery atherosclerosis
  • Planned major surgery or invasive intervention
  • Active internal bleeding
  • Malignancy or other serious medical conditions with a life expectancy \<6 months
  • Allergery to Rivaroxaban
  • Pregnancy or breast-feeding

Key Trial Info

Start Date :

January 18 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2024

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT03772457

Start Date

January 18 2019

End Date

December 31 2024

Last Update

April 18 2023

Active Locations (1)

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Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China, 310009