Status:

RECRUITING

CNS Changes Following SCI

Lead Sponsor:

University of Zurich

Conditions:

Spinal Cord Injuries

Eligibility:

All Genders

18-75 years

Brief Summary

The objective of this study is to better understand the structural and functional changes that the central nervous system (CNS) undergoes following spinal cord injury and how these changes relate to c...

Eligibility Criteria

Inclusion

  • Inclusion Criteria - Patients:
  • Age 18-75
  • Traumatic or non-traumatic spinal cord injury (para- and tetraplegia)
  • Acute (\<4 weeks post SCI) to chronic SCI (\> 6 months post SCI)
  • Signed informed consent
  • Exclusion Criteria - Patients:
  • Contraindications to magnetic resonance imaging
  • Neurological impairment of body function impairments not induced by spinal cord injury
  • BMI \> 40
  • Pregnancy
  • Claustrophobia
  • Inclusion Criteria - Healthy subjects:
  • Age 18-75
  • Signed Informed consent
  • Exclusion Criteria - Healthy subjects:
  • Contraindications to magnetic resonance imaging
  • Pregnancy
  • Neurological illness
  • Impairment of body function induced by a spinal cord injury
  • Claustrophobia
  • BMI \> 40

Exclusion

    Key Trial Info

    Start Date :

    July 18 2018

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 30 2027

    Estimated Enrollment :

    450 Patients enrolled

    Trial Details

    Trial ID

    NCT03772548

    Start Date

    July 18 2018

    End Date

    June 30 2027

    Last Update

    December 15 2025

    Active Locations (1)

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    1

    Universitätsklinik Balgrist

    Zurich, Switzerland, 8008