Status:
UNKNOWN
MRI Maker of Perioperative Neurocognitive Disorder
Lead Sponsor:
RenJi Hospital
Conditions:
Necrosis of Femoral Head
Knee Osteoarthritis
Eligibility:
All Genders
60+ years
Brief Summary
Periperative neurocognitive disorder(PND) is consistently associated with increased morbidity and mortality, but its mechanisms remain unclear. Moreover, valid biomarkers for the prediction or diagnos...
Eligibility Criteria
Inclusion
- Age ≥ 60 years
- Spoke proficient Chinese
- Selected to lower limb osteopathic surgery
- Informed consent signed by the patient
- Underwent general anesthesia
Exclusion
- Existing cerebral disease, or have a history of neurological and psychiatric diseases including AD, stroke, and psychosis
- Existing cognitive impairment as evidenced by Mini-Mental State Examination scores below 24
- Several audition or vision disorder
- With standard contraindications to MRI examinations
- Unwillingness to comply with the protocol or procedures.
Key Trial Info
Start Date :
December 12 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 30 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03773627
Start Date
December 12 2018
End Date
July 30 2020
Last Update
December 13 2018
Active Locations (1)
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1
Renji Hospital
Shanghai, Shanghai Municipality, China, 200127