Status:
COMPLETED
PET-FDG in Myocarditis
Lead Sponsor:
Montreal Heart Institute
Conditions:
Myocarditis
Viral Myocarditis
Eligibility:
All Genders
18+ years
Brief Summary
This study evaluates the diagnostic performance of 18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) with rest perfusion imaging for the...
Detailed Description
Myocarditis is characterized by myocardial inflammation, which can lead to fibrosis and heart failure. FDG PET/CT, with appropriate suppression protocol including high-fat-low-carbohydrate diet, fast...
Eligibility Criteria
Inclusion
- 18 years of age or older
- Clinical suspicion of myocarditis due to findings such as:
- Symptoms and signs of myocarditis such as dyspnea, orthopnea, palpitation, and chest pain, without other identifiable cause
- New onset of cardiovascular symptoms with recent history of viral disease or previous myocarditis
- Unexplained new onset of left ventricular dysfunction
- Unexplained elevated troponin
- Magnetic resonance imaging findings suggestive of myocarditis, such as late gadolinium enhancement and edema
- Biopsy findings compatible with myocarditis
- Women of childbearing potential must have a negative urine or blood pregnancy test
- Capable of giving informed consent and the consent must be obtained prior to any study related procedures
- Subject's with body mass index inferior or equal to 45 kg/m2
Exclusion
- Female subject who is pregnant or breastfeeding and unwilling to stop for 24h
- Claustrophobia or inability to lie still in a supine position for imaging purposes
- Unwillingness or inability to provide informed consent
Key Trial Info
Start Date :
November 20 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 31 2024
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03777839
Start Date
November 20 2018
End Date
August 31 2024
Last Update
November 22 2024
Active Locations (1)
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1
Matthieu Pelletier-Galarneau
Montreal, Quebec, Canada, H3L3C1