Status:

COMPLETED

The Efficacy and Safety of Early Vitamin AD Supplementation in Very Preterm Infants

Lead Sponsor:

Zhengzhou Children's Hospital, China

Conditions:

Efficacy and Safety

Eligibility:

All Genders

1-96 years

Phase:

NA

Brief Summary

Bronchopulmonary dysplasia (BPD) is the most prevalent longterm morbidity among surviving extremely preterm infants and has a multifactorial etiology. BPD is associated with later risk of reactive air...

Eligibility Criteria

Inclusion

  • gestational age\<32 weeks,
  • \<96 hours of age

Exclusion

  • genetic metabolic diseases;
  • congenital major abnormalities;
  • congenital non-bacterial infection with overt signs at birth;
  • terminal stage of illness (pH \< 7.0 or hypoxia with bradycardia\>2 h);
  • ≥ grade III intracranial hemorrhage;
  • lacking parental consent.

Key Trial Info

Start Date :

July 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 28 2020

Estimated Enrollment :

676 Patients enrolled

Trial Details

Trial ID

NCT03779776

Start Date

July 1 2018

End Date

June 28 2020

Last Update

September 10 2021

Active Locations (1)

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Zhengzhou Children's Hospital

Zhengzhou, Henan, China, 450018