Status:
RECRUITING
Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia
Lead Sponsor:
University of Arizona
Collaborating Sponsors:
Sidney R. Baer, Jr. Foundation
Conditions:
Schizophrenia
Eligibility:
All Genders
18-40 years
Phase:
PHASE1
Brief Summary
Schizophrenia is a severe psychotic illness of unknown cause that affects 1% of the population worldwide. Currently, there is no diagnostic test for schizophrenia. Instead, the diagnosis is typically ...
Detailed Description
The overall objective of the study is to test the hypothesis that patients with schizophrenia will have a heightened tolerance to the sedating effects of antipsychotic medications, which will be refle...
Eligibility Criteria
Inclusion
- Inclusion Criteria Healthy Control
- Be between 18 and 40 years of age
- Be able to understand English
- Have no history of psychosis
- Have no history of sleep apnea, heart condition or seizure
- Have no known drug allergies
- The ability to swallow a pill
- Exclusion Criteria Healthy control
- Refuse to sign the consent form
- Drink caffeine or alcohol within 24 hours of the study
- Have the EKG readout report borderline or abnormal ECG
- Have the 12 panel urine drug screen show a positive result
- Be pregnant
- Inclusion Criteria Schizophrenic subject
- Be between 18 and 40 years of age
- Be able to understand English
- Have been diagnosed with a Schizophrenia Spectrum or other psychotic disorder
- Belong to one of three groups:
- Never medicated patients with a first episode of psychosis
- Have not received long acting injectable (depot) antipsychotic in previous 6 months
- Have not received oral antipsychotic (or antidepressant that has serotonergic action) in previous 2 weeks
- Have no history of sleep apnea, heart condition or seizure
- Have no known drug allergies
- Be able to swallow a pill
- Healthy as determined by the enrolling physician(s)
- Exclusion Criteria Schizophrenic subject
- Refuse to sign the consent form
- Drink caffeine or alcohol within 24 hours of the study
- Have the EKG readout report borderline or abnormal ECG
- Have the 12 panel urine drug screen show a positive result
- Be pregnant
Exclusion
Key Trial Info
Start Date :
November 20 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 10 2026
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT03781115
Start Date
November 20 2017
End Date
February 10 2026
Last Update
June 3 2025
Active Locations (1)
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1
Banner University Medical Center
Phoenix, Arizona, United States, 85006