Status:
UNKNOWN
Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate Pleurodesis
Lead Sponsor:
Assiut University
Conditions:
Pleural Effusion, Malignant
Eligibility:
All Genders
30-75 years
Phase:
PHASE1
PHASE2
Brief Summary
The primary goal of this study is to compare well-defined pleural effusion management success outcomes in patients with malignant or paramalignant pleural effusions who were treated with Indwelling pl...
Detailed Description
Dyspnea is present in 50% of patients with malignant pleural effusion and quality of life is significantly impaired. Chemical pleurodesis using various sclerosing agents is accepted as a palliative t...
Eligibility Criteria
Inclusion
- Unilateral symptomatic recurrent malignant pleural effusion patients who fulfill the criteria for pleurodesis (i.e. positive pleural biopsy or cytology for malignancy, a Karnofsky index score of more than 60 and life expectancy of more than one year).
- Rapidly accumulated undiagnosed pleural effusion .
- Age : 30-75 years old.
Exclusion
- Transudative pleural effusion.
- Exudative pleural effusion due to causes other than malignancy ( i.e. parapnuemonic , post-tuberculous pleural effusion )
- Presence of hemorrhagic diathesis ( prothrombin time \<50% and platelet count \<80,000/mm 3 )
- Active pleural or systemic infection.
- Neoplastic infiltration of the skin at the site of pleural catheter insertion.
- Malignant pleural effusion with trapped lung or loculated pleural effusion.
- Previous lobectomy or pneumonectomy on the affected side.
- Karnofsky index score\> 50.
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2020
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT03781908
Start Date
January 1 2019
End Date
January 1 2020
Last Update
December 20 2018
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.