Status:
COMPLETED
Investigation of Microbiome-Derived Metabolite Production in Response to a Mediterranean Diet
Lead Sponsor:
Laval University
Conditions:
Food Habits
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
This project proposes to characterise the microbiome-derived metabolites produced upon ingestion of bioactive precursor-rich meals by healthy volunteers in order to investigate the relationship betwee...
Detailed Description
There is a large inter-individual variability in gut microbiome-derived metabolites production upon ingestion of similar meals. Since many of these microbiome-derived metabolites have enteric and syst...
Eligibility Criteria
Inclusion
- Men and women aged between 18 and 35 years
- Body mass index between 18.5 and 30 kg/m2
- General good health
- Computer and Internet access
- Basic understanding of written French
Exclusion
- Intestinal pathologies including inflammatory bowel disease and gastrointestinal cancers
- Pregnant and/or breast-feeding women
- Alcohol consumption greater than 15 portions for men and 10 for women weekly
- Active tobacco usage
- Consumption of dietary supplements (e.g. multivitamins, omega-3, probiotics)
- Completion of a course of antibiotics in the past 3 months
- Regular use of anti-inflammatory drugs, or use in the past 3 months
- Important weight change (+/- 5 kg) in the past 6 months
- Allergies or food intolerances to ingredients present in trial diets
Key Trial Info
Start Date :
January 7 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2019
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT03783260
Start Date
January 7 2019
End Date
December 1 2019
Last Update
February 28 2020
Active Locations (1)
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1
Institut sur la nutrition et les aliments fonctionnels - INAF
Québec, Quebec, Canada, G1V 0A6