Status:
COMPLETED
Effects of Hypericum Perforatum Oil on Promoting Skin Recovery in Different Human Skin Damage Models
Lead Sponsor:
University of Split, School of Medicine
Conditions:
Skin Recovery in Different Human Skin Damage Models
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Saint John's wort (Hypericum perforatum) was recognised as a traditional, folk medicine used topically for the treatment of wounds, abrasions, burns, sunburns and inflammatory skin disorders. Its use...
Eligibility Criteria
Inclusion
- \- young, healthy volunteers who gave written informed consent
Exclusion
- skin disease, skin damage on measurement sites
- use of corticosteroids, antihistamines and immunomodulators a month prior the inclusion and during the trial
- use of drugs that may cause photosensitivity
- use of emollients three days prior the inclusion in the trial
- non-adherence to the trial protocol
- exposure to artificial and excessive natural UV radiation
- pregnancy and lactation
- skin cancer
- history of vitiligo, melasma and other pigmentation and photosensitivity disorders
- immunosuppression
- allergic or irritant reactions to the constituents of the two ointments (active and placebo) and similar chemicals (e.g. salicylic and benzoic acid)
Key Trial Info
Start Date :
February 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 29 2019
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT03783819
Start Date
February 4 2019
End Date
March 29 2019
Last Update
February 21 2020
Active Locations (1)
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1
School of Medicine
Split, Croatia, 21000