Status:
COMPLETED
Melatonin Plus Aminoacids for Sarcopenic Elderly
Lead Sponsor:
Azienda di Servizi alla Persona di Pavia
Conditions:
Sarcopenia
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
To evaluate the effectiveness of melatonin and essential aminoacid supplementation on body composition, protein metabolism, strength and inflammation. The investigators performed a Randomized controll...
Eligibility Criteria
Inclusion
- Aged \> or equal 65 years
- Sarcopenic patients, following the Rosetta Study criteria: Skeletal Muscle Index \[SMI\] was \<7.23 kg/m2 in men and \<5.45 kg/m2 in women) and loss of strength, evaluated by dynamometer and defined as \<30 kg for men and \<20 kg for women, using the average value of the two handgrip measurements of the dominant hand.
Exclusion
- acute illnesses
- severe liver dysfunction
- severe heart dysfunction
- severe kidney dysfunction
- severe dementia
- uncontrolled diabetes
- dysthyroidism
- any endocrinopathies
- neoplasia
- patients treated with steroids
- patients entirely unable to walk
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2015
Estimated Enrollment :
159 Patients enrolled
Trial Details
Trial ID
NCT03784495
Start Date
January 1 2014
End Date
June 1 2015
Last Update
December 24 2018
Active Locations (1)
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1
Geriatric physical medicine and rehabilitation division at the Istituto Santa Margherita - Azienda di Servizi alla Persona di Pavia
Pavia, Italy, 27100