Decentrialz logo
  • HIPAA Compliant
  • ISO 27001 Certified
Find Trials
About UsContact
Become a Volunteer+1 877 705 1914

Status:

TERMINATED

Visualizing Beta Cells After Islet Transplantation

Lead Sponsor:

Radboud University Medical Center

Conditions:

Type 1 Diabetes Mellitus

Eligibility:

All Genders

18+ years

Brief Summary

In patients with type 1 diabetes (T1D) that have undergone islet of Langerhans transplantation or are on the waiting list for transplantation, Ga-68-exendin PET imaging is performed to study the visua...

Detailed Description

Detecting damage to islets with a reliable imaging technique could be important for improving islet survival after transplantation. This could lead to better patient outcomes which would be of great i...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Tx-group:
  • \>18 years old
  • T1D patient undergone islet transplantation
  • Clinically proven functional islet graft
  • Signed informed consent
  • Control group:
  • \>18 years old
  • T1D patients who are on the waiting list for islet transplantation
  • Signed informed consent
  • Exclusion Criteria:
  • Treatment with synthetic exendin or Dipeptidyl-Peptidase IV inhibitors within the last 3 months
  • Breast feeding
  • Pregnancy or the wish to become pregnant within 6 months
  • Kidney disease
  • Liver disease
  • Age \<18 years
  • No signed informed consent
  • Exclusion criteria for MR:
  • fragments, clips or devices in brain, eyes, spinal canal
  • Implantable defibrillator or pacemaker (wires)
  • Mandibular magnetic implants
  • Neurostimulator, bladder stimulator, non-removable insulin pump
  • Metal tissue-expander in chest
  • Cochlear implant
  • Ossicular replacement prosthesis

Exclusion

    Key Trial Info

    Start Date :

    June 6 2016

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    May 27 2021

    Estimated Enrollment :

    13 Patients enrolled

    Trial Details

    Trial ID

    NCT03785236

    Start Date

    June 6 2016

    End Date

    May 27 2021

    Last Update

    February 14 2022

    Active Locations (2)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (2 locations)

    1

    Radboud university medical center

    Nijmegen, Gelderland, Netherlands, 6525 GA

    2

    Uppsala University Hospital

    Uppsala, Sweden, SE-751 85