Status:
COMPLETED
Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight
Lead Sponsor:
University of Pennsylvania
Collaborating Sponsors:
University of Pittsburgh
National Aeronautics and Space Administration (NASA)
Conditions:
Resilience
Mood
Eligibility:
All Genders
30-55 years
Phase:
NA
Brief Summary
This study assesses differences in biological and behavioral domains that relate to individual adaptation and resiliency to an isolated, confined and controlled environment, and evaluates the effect o...
Detailed Description
The goal of this study is to obtain novel information that will be used to help identify individuals who are resilient to the stressors of prolonged human spaceflight, thereby encouraging the successf...
Eligibility Criteria
Inclusion
- Age between 30 and 55 years
- A master's degree (or its equivalency in work experience) in Science, Technology, Engineering and Math (STEM) or military service
- Free of psychological/psychiatric conditions that preclude participation
- BMI \< 35
- Ability to read/write English
Exclusion
- History of neurological, psychiatric, or other medical condition that excludes participation
- Current mania or psychosis
- Current depression
- Current poor resiliency
- Alcohol or drug abuse in the past year based upon history and urine toxicology screen.
- Current smoker/tobacco user.
- Acute, chronic, or debilitating medical conditions, major Axis I psychiatric illness, epilepsy, or thyroid disease based
- Cardiovascular, neurological, gastrointestinal, or musculoskeletal problems that exclude participation
- For MRI testing any of the following conditions may exclude subjects from participation in the present experiment: Tinnitus; sensorineural hearing loss \> 30 decibels; pace maker or internal defibrillator; metallic implants (e.g. orthopedic plates after bone fractures, joint replacements, surgical staples or clips, artificial heart valves, stents, cava filters); metallic splinters (e.g. after an accident or due to war injury); non-removable dental brace; tattoo (some tattoo inks contain metallic particles); permanent make-up; intrauterine contraceptive device; cochlear implant (implanted hearing device); medication pump; acupuncture needle; other foreign bodies/objects which are non-removable; pregnancy (or its possibility); previous brain and/or heart surgery; and fear of tight spaces.
Key Trial Info
Start Date :
February 22 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2025
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT03786016
Start Date
February 22 2019
End Date
February 28 2025
Last Update
April 6 2025
Active Locations (1)
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1
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104