Status:
UNKNOWN
Postmenopausal Women With Vaginal Microbiota
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
HPV-Related Squamous Cell Carcinoma
Eligibility:
FEMALE
20-75 years
Brief Summary
Since other genital infections enhance HIV susceptibility by inducing inflammation, the investigators study the relationship between the vaginal microbiota composition and the risk of HPV infection, c...
Detailed Description
Persistent infection with oncogenic Human Papillomavirus (HPV) is necessary but not sufficient for the development of cervical cancer. Additional factors correlated with HPV persistence include immuno...
Eligibility Criteria
Inclusion
- Those are aged 20 to 75 years old, have had vaginal intercourse more than 3 years, and aren't in menstrual, pregnancy or puerperium period.
Exclusion
- Those have no vaginal intercourse, and can't cooperate the examiner. Women who are HIV or hepatitis B/C positive, have autoimmune disorders and systemic disease (like diabetes mellitus, hormone treatment diseases, severe liver and kidney dysfunction), or have severe mental illness and malignant tumors are also excluded. At the same time, all the participants should meet the following requirements: no vagina douching within last 2 days, no vaginal intercourse within last 3 days, no systemic application of antifungal agents or antibiotics or pessaries within last 14 days of sampling.
Key Trial Info
Start Date :
December 25 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2020
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT03786601
Start Date
December 25 2018
End Date
July 1 2020
Last Update
August 29 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730