Status:
COMPLETED
The Association of Cardiac Ion Channel Related Gene Polymorphism and Prolonged QTc Interval After Endotracheal Intubation
Lead Sponsor:
Yonsei University
Conditions:
Emergence Delirium
Eligibility:
All Genders
20-65 years
Brief Summary
The QTc interval is affected by heart rate, medications and changes in the autonomic nervous system. The endotracheal laryngoscopy, the necessary step during general anesthesia, prolongs QTc interval....
Eligibility Criteria
Inclusion
- 20-65 years old
- scheduled for general anesthesia requiring direct laryngoscopy
Exclusion
- Patients taking antihypertensive medication (beta-blocker, CCB)
- patients taking other medications known to affect QTc interval
- Patients with abnormal ECG and prolonged QTc (\>500 msec)
- Diabetes, liver disease, kidney disease, heart failure, congenital heart disease
- Severe electrolyte imbalance
- illiterate, foreigners who cannot understand the consent form
Key Trial Info
Start Date :
September 24 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 3 2020
Estimated Enrollment :
315 Patients enrolled
Trial Details
Trial ID
NCT03788564
Start Date
September 24 2017
End Date
May 3 2020
Last Update
September 29 2020
Active Locations (1)
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1
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine
Seoul, South Korea, 120-752