Status:
UNKNOWN
Evaluation of Inflammation Activity in Ulcerative Colitis by pCLE
Lead Sponsor:
Shandong University
Conditions:
Inflammation
Eligibility:
All Genders
18-80 years
Brief Summary
The aim:1) To test the correlation of pCLE-obtained features with histological findings in UC; comparing the real-time conventional colonoscopy Baron score with CLE assessment. 2) To test the accuracy...
Detailed Description
Patients with acute inflammatory infiltrates seen on histological assessment are more likely to experience relapse than are those without infiltrates,studies suggest that severity of inflammation is a...
Eligibility Criteria
Inclusion
- Male or Female aged 18-80;
- patients previously or in-process diagnosed as Ulcerative Colitis
Exclusion
- Patients with gastrectomy, acute GI bleeding, and advanced esophageal cancer;
- Patients under conditions unsuitable for performing CLE including coagulopathy (prothrombin time \<50% of control, partial thromboplastin time \>50 s), lactation, food retention, oesophageal stenosis, postoperative cases, leiomyoma, impaired renal function (creatinine level \>1.2 mg/dL), pregnancy or breastfeeding, and known allergy to fluorescein sodium;
- Inability to provide informed consent and other situations that could interfere with the examination protocol.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2019
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03788824
Start Date
June 1 2014
End Date
February 1 2019
Last Update
December 28 2018
Active Locations (1)
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1
Department of Gastroenterology, Qilu Hospital, Shandong University
Jinan, Shandong, China, 250012