Status:
COMPLETED
Dydrogesterone in the Treatment of Endometrial Polyps
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Endometrial Polyp
Eligibility:
FEMALE
20-50 years
Phase:
PHASE4
Brief Summary
This study is intended to observe the therapeutic effect of dydrogesterone on endometrial polyps and provide a reference for clinical treatment.
Detailed Description
Endometrial polyps are a common female endometrial lesion.The long-term unrestrained exposure of estrogen to local tissue is one of the causes of polyp formation.Studies suggested that the progesteron...
Eligibility Criteria
Inclusion
- women of childbearing age from 20 to 50 years old
- with or without menstrual changes:
- menostaxis (longer than 7 days)
- shortened menstrual cycles(less than 23 days)
- menorrhagia(more than twice as much as usual)
- abnormal vaginal bleeding(non-menstrual vaginal bleeding)
- with following signs of vaginal ultrasound in the follicular phase (day 1 to day 10 of a menstrual cycle):
- typical signs with a suspect of EP: (median/high) echo with a regular contour within the uterine lumen;
- atypical signs with a suspect of EP: punctate cystic areas within the endometrium and the endometrial thickness \>1cm;
Exclusion
- no menses within half a year;
- surgery or drug treatment of endometrial lesions in the past half year;
- with current intrauterine device;
- combined with other acute gynecological inflammation;
- with clinically suspected malignant tumors;
- long-term use of oral contraceptives;
- with abnormal liver and kidney function;
- with benign or malignant breast tumors;
- with any systemic malignant tumor or a history of tumors;
- participants who are pregnant.
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03790215
Start Date
February 1 2019
End Date
December 31 2019
Last Update
January 22 2020
Active Locations (1)
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1
Peking Union Medical College Hospital
Beijing, China, 100730