Status:

UNKNOWN

Study to Evaluate the Safety and Efficacy of the Cytrellis Micro-Coring Device for the Treatment of Moderate to Severe Facial Wrinkles

Lead Sponsor:

Cytrellis Biosystems, Inc.

Conditions:

Wrinkle

Eligibility:

All Genders

40-70 years

Phase:

NA

Brief Summary

Study evaluating the efficacy of a micro coring device for the treatment of moderate to severe check wrinkles

Detailed Description

Up to 35 subjects who meet the inclusion/exclusion criteria will be treated. All subjects will be monitored for a period of 90 days post treatment. Study results will be assessed with the following: ...

Eligibility Criteria

Inclusion

  • Males and females 40-70 years of age
  • Fitzpatrick Skin Type I to IV as judged by the Investigator
  • Cheek areas are at least a score of 3 using the Lemperle Wrinkle Assessment Scale as judged by the Investigator
  • Able to provide written informed consent, understand and willing to comply with all study related procedures and follow-up visits.

Exclusion

  • Lesions suspicious for any malignancy or the presence of actinic keratosis, melasma, vitiligo, cutaneous papules/nodules or active inflammatory lesions in the areas to be treated
  • History of keloid formation or hypertrophic scarring
  • History of trauma or surgery to the treatment areas in the past 6 months
  • Scar present in the areas to be treated
  • Silicone injections in the areas to be treated
  • Injection of dermal fillers, fat or botulinum toxin, as well as any minimally invasive/invasive medical device for skin treatment, in the study treatment areas, within the past 6 months (i.e., dermabrasion, laser, RF devices)
  • Active smokers (0.5 pack/day) or having quit within 3 months prior to treatment
  • Active, chronic, or recurrent infection
  • History of compromised immune system or currently being treated with immunosuppressive agents
  • History of sensitivity to analgesic agents, Aquaphor®, topical or local anesthetics (e.g., lidocaine, benzocaine, procaine) or chlorhexidine, povidone-iodine or epinephrine
  • Excessive sun exposure and use of tanning beds or tanning creams within 30 days prior to treatment
  • Treatment with aspirin or other blood thinning agents within 14 days prior to treatment
  • History or presence of any clinically significant bleeding disorder
  • Any issue that, at the discretion of the Investigator, would interfere with assessment of safety or efficacy or compromise the subject's ability to participate in the study
  • Treatment with an investigational device or agent within 30 days before treatment or during the study period

Key Trial Info

Start Date :

November 12 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 21 2019

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT03793348

Start Date

November 12 2018

End Date

August 21 2019

Last Update

January 4 2019

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Laser and Skin Surgery Center of Northern California

Sacramento, California, United States, 95816

2

AboutSkin Research, LLC

Greenwood Village, Colorado, United States, 80111

3

Miami Dermatology & Laser Institute

Miami, Florida, United States, 33173

4

Laser and Skin Surgery of New York

New York, New York, United States, 10016