Status:
COMPLETED
Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction
Lead Sponsor:
Tata Main Hospital
Conditions:
Cognitive Dysfunction
Eligibility:
All Genders
60-75 years
Phase:
PHASE4
Brief Summary
This study will aim to identify the impact of Intraoperative dexmedetomidine infusion on POCD assessed by the Montreal Cognitive Assessment (MoCA) in geriatric patients above 60 years undergoing hip s...
Detailed Description
Postoperative cognitive dysfunction (POCD) is a common postoperative neurological complication in elderly. POCD is a subtle impairment of memory, concentration and information processing with clinical...
Eligibility Criteria
Inclusion
- American society of Anesthesiology (ASA) status of I-III
- Age between 60-75 years scheduled for elective hip surgery under spinal anesthesia
Exclusion
- Patient not willing to be a part of the study
- Patients were aged \<60 or \>75 years
- Patients with accompanying medical conditions that may affect the level of consciousness, such as stroke, stupor or dementia, or patients with abnormalities in hepatic or renal function, electrolyte imbalance
- Patients suffering from preoperative bradycardia \[heart rate (HR) \<60 bpm\] or hypotension \[mean arterial blood pressure (MAP) \<70 mmHg\]
- Patients who had recently received a sedative or opioid drug
- Patients with a MoCA (Montreal Cognitive Assessment) score \<26
- Patients with persistent hypotension and bradycardia intra-operatively even after giving Mephentermine will be excluded from the study
Key Trial Info
Start Date :
October 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2019
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03793751
Start Date
October 1 2017
End Date
December 1 2019
Last Update
September 19 2024
Active Locations (1)
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1
Dr.Deb Sanjay Nag
Jamshedpur, Jharkhand, India, 831011