Status:
COMPLETED
Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Lead Sponsor:
University of Michigan
Conditions:
Acute Respiratory Distress Syndrome
ARDS
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Doctors follow a standard ventilator management strategy when making adjustments to the breathing machine to optimize the amount of oxygen into the lungs. The purpose of this study is to assess whethe...
Eligibility Criteria
Inclusion
- Endotracheal ventilation for \< 1 week (168 hours)
- Presence of all of the following conditions for \< 48 hours i. Partial pressure of oxygen to percentage of inspired oxygen (PaO2/FiO2) \< 150 with PEEP \> 5 cm water for \> 30 min.
- ii. bilateral opacities not fully explained by effusions, lobar/lung collapse, or nodules iii. respiratory failure not fully explained by cardiac failure or fluid overload
- All criteria listed in (3) developed within 1 week of a known clinical insult or new or worsening respiratory symptoms
Exclusion
- Lack of informed consent
- Known pregnancy
- Extracorporeal membrane oxygenation (ECMO) use
- Severe chronic respiratory disease requiring home oxygen therapy or ventilation
- Calculated BMI of greater than 50
Key Trial Info
Start Date :
March 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 24 2022
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT03793842
Start Date
March 4 2019
End Date
June 24 2022
Last Update
October 12 2023
Active Locations (1)
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1
The University of Michigan
Ann Arbor, Michigan, United States, 48109