Status:
COMPLETED
Positive End-expiratory Pressure (PEEP) in Predicting Fluid Responsiveness in Patients Undergoing One-lung Ventilation
Lead Sponsor:
Hallym University Kangnam Sacred Heart Hospital
Conditions:
Lung Cancer
Lung Diseases
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The present study is to evaluate the effect of positive end-expiratory pressure (PEEP) in predicting fluid responsiveness in patients undergoing one-lung ventilation.
Detailed Description
Appropriate fluid challenge is crucial during lung surgery under one-lung ventilation. Applying PEEP in mechanically ventilating patients changes dynamic hemodynamic parameters (stroke volume variatio...
Eligibility Criteria
Inclusion
- patients undergoing lung surgery under one-lung ventilation
Exclusion
- arrhythmia
- moderate to severe valvular heart disease moderate to severe pericardial effusion left ventricular ejection fraction \< 40%
- moderate to severe chronic obstructive lung disease
- unable to insert oesophageal Doppler Monitor (ODM) probe ( esophageal stent, esophageal cancer, previous esophageal surgery, esophageal stricture, esophageal varices, pharyngeal pouch and severe coagulopathy )
- patient refusal
- cannot understand the protocol
- less than 50kg or over 100kg in weight
Key Trial Info
Start Date :
January 31 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 26 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03794414
Start Date
January 31 2019
End Date
June 26 2020
Last Update
July 29 2020
Active Locations (1)
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1
Kangnam Sungshim Hospital
Seoul, South Korea