Status:

UNKNOWN

Multi-omics Study of Clinical Endpoints in CHD

Lead Sponsor:

Guangdong Provincial People's Hospital

Collaborating Sponsors:

RenJi Hospital

West China Hospital

Conditions:

Coronary Heart Disease

Eligibility:

All Genders

18-80 years

Brief Summary

This study aimed to explore underlying mechanisms of individual differences in drugs for coronary heart disease treatment and its association with adverse consequences. It will enroll approximately 40...

Detailed Description

The study is a multicenter prospective cohort study, aimed to explore underlying mechanisms of individual differences in drugs for coronary heart disease treatment and its association with adverse con...

Eligibility Criteria

Inclusion

  • age: 18-80 years
  • Chinese Han patients with coronary artery disease
  • inpatients undergoing coronary angiography or percutaneous coronary intervention

Exclusion

  • renal insufficiency (defined as serum creatinine concentration \> 2 times the upper limit of normal \[230 μmol/L\], renal transplantation or dialysis)
  • hepatic insufficiency (defined as serum transaminase concentration \> 2 times the upper limit of normal \[80 U/L\], or a diagnosis of cirrhosis)
  • pre-existing bleeding disorders
  • being pregnant or lactating
  • advanced cancer or haemodialysis
  • history of thyroid problems, and use of antithyroid drugs or thyroid hormone medication
  • incomplete information about cardiovascular events during follow-up

Key Trial Info

Start Date :

July 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2020

Estimated Enrollment :

4000 Patients enrolled

Trial Details

Trial ID

NCT03797339

Start Date

July 1 2017

End Date

December 31 2020

Last Update

February 12 2019

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Guangdong General Hospital

Guangzhou, Guangdong, China, 510080

2

The First Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510080

3

XiangYa Hospital Central South University

Changsha, Hunan, China, 410008

4

Renji Hospital Affiliated to Shanghai Jiaotong University

Shanghai, Shanghai Municipality, China, 200233