Status:
COMPLETED
Nutritional Supplements and Performance During Visual Field Testing (B3 Vitamin)
Lead Sponsor:
Columbia University
Conditions:
Visual Field Defect, Peripheral
Glaucoma, Open-Angle
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
This study seeks to test whether these over-the-counter nutritional supplements have an impact on patients' performance during visual field testing.
Detailed Description
Glaucoma is the leading cause of irreversible blindness worldwide. The most important test to detect progression is visual field testing. Visual field testing is the reference standard to measure visu...
Eligibility Criteria
Inclusion
- Confirmed diagnosis of primary open-angle glaucoma;
- Visual field loss on 24-2 standard automated perimetry (SAP) worse than -3 decibels (dB) and better than -12 dB in both eyes;
- Best corrected visual acuity better than 20/40 in both eyes;
- Prior experience with 24-2 visual fields (at least 3 tests done in the past 3 years).
Exclusion
- Significant cataract or media opacity;
- Diagnosis of dementia, Alzheimer's, and other neurological diseases;
- Current use or use in the past 1 month of nutritional supplements;
- Inability to take or intolerance to nicotinamide and/or pyruvate.
Key Trial Info
Start Date :
April 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT03797469
Start Date
April 15 2019
End Date
December 31 2020
Last Update
November 11 2021
Active Locations (1)
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1
Columbia University Medical Center
New York, New York, United States, 10032