Status:
UNKNOWN
Biochemical Versus Ultrasound Findings as Predictors of Fetal Loss in Cases of First Trimester Threatened Miscarriage
Lead Sponsor:
Ain Shams University
Conditions:
Abortion Threatened
Eligibility:
FEMALE
20-35 years
Phase:
NA
Brief Summary
Threatened miscarriage occurs in about one-fifth of pregnancies with an estimated miscarriage rate of 3-16% after successful demonstration of fetal cardiac activity. Various biochemical markers have b...
Detailed Description
we are comparing between the accuracy of vaginal ultra sound versus serum progesterone level and serum CA 125 level in predicting of fetal demise in cases of threatened miscarriage three vaginal ultra...
Eligibility Criteria
Inclusion
- Singleton Pregnancy.
- Age20-35years.
- Gestational age between6 to 8weeks.
- Threatened miscarriage is diagnosed by vaginal bleeding, closed cervix and positive fetal life.
- Patients who are sure of their dates (three regular menstrual cycles before conception without the use of hormonal contraception.
Exclusion
- Patients with recurrent miscarriage or pregnancy of unknown location (PUL).
- Patients had ovulation induction medications or on progesterone treatment.
- Patients with past medical history of diabetes mellitus or chronic hypertension.
- Patients who are unsure of the last menstrual period date or with irregular menstrual cycle.
- Pregnancy associated with presence of ovarian cyst.
- Molar pregnancy.
- Those who had a history of maternal disease which would cause an increase in CA-125level. These diseases include chronic pelvic infection, endometriosis, myoma uteri, endometrioma and lung, kidney and hepatic diseases.
Key Trial Info
Start Date :
December 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2019
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT03797508
Start Date
December 1 2018
End Date
September 30 2019
Last Update
February 5 2019
Active Locations (1)
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1
Ain Shams University
Cairo, Egypt