Status:
COMPLETED
Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project
Lead Sponsor:
VA Office of Research and Development
Conditions:
Cocaine Use Disorder
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The proposed work will investigate changes in brain signaling and cognitive functioning that support recovery from addiction, as well as use of pretreatment neurocognitive functioning to inform substa...
Detailed Description
Electrophysiological methods, including event-related potential and functional connectivity approaches, have potential to clarify mechanisms of substance use treatment response and characterize indivi...
Eligibility Criteria
Inclusion
- Military Veterans
- DSM-5 Criteria for Cocaine Use Disorder (Mild, Moderate, or Severe)
- Cocaine Use Within Past 60 Days
- Stated Goal of Cocaine Abstinence or Reduced Cocaine Use
- Normal or Corrected-to-Normal Vision
- Average or Corrected Hearing
Exclusion
- History of Severe Traumatic Brain Injury, Seizure Disorder, or other Neurological Illness
- Severe or Unstable Medical or Psychiatric Condition
- Pregnant or Lactating Women
- Moderate-to-Severe Neurocognitive Impairment per Medical Record, SLUMS \< 21, or Mini MoCA \< 11
- In Ongoing Residential Treatment or Imminently Expected to Enter Residential Treatment During the Study Interval at Time of Screening
Key Trial Info
Start Date :
November 13 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 12 2024
Estimated Enrollment :
63 Patients enrolled
Trial Details
Trial ID
NCT03799341
Start Date
November 13 2019
End Date
April 12 2024
Last Update
September 30 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Pittsburgh, Pennsylvania, United States, 15240