Status:
COMPLETED
Bisoprolol Versus Corticosteroid and Bisoprolol Combination for Prophylaxis Against Atrial Fibrillation After on Pump Coronary Artery Bypass Surgery
Lead Sponsor:
Ain Shams University
Conditions:
Prevention
Atrial Fibrillation
Eligibility:
All Genders
40-79 years
Phase:
PHASE4
Brief Summary
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia that occurs after on pump coronary artery bypass graft (CABG) surgery. It is associated with postoperative complications, inc...
Detailed Description
The study was conducted at The Cardiothoracic surgery intensive care unit of Ain Shams University hospitals during a period of 6 months. The study protocol was approved by "research and ethics committ...
Eligibility Criteria
Inclusion
- \- .176 Patients were registered in the study.
- .Range of age between 40 and 79 years old .Undergoing elective on pump CABG operations without concomitant procedures.
Exclusion
- : Patients with preoperative rhythm abnormalities (sick sinus syndrome,
- atrioventricular conduction abnormalities,
- history of chronic or intermittent AF),
- pretreatment with classes I and III antiarrhythmic agents,
- receiving anti-hypertensive drugs except angiotensin convertor enzyme (ACE) inhibitors,
- thyroid disease,
- renal or liver disease,
- peripheral arterial atherosclerotic disease,
- thrombophlebitis,
- uncontrolled diabetes mellitus,
- systemic bacterial or mycotic infection,
- active tuberculosis,
- Cushing's syndrome,
- peptic ulcer,
- psychotic mental disorder,
- Herpes Simplex keratitis
- chronic obstructive pulmonary disease were not included in the study.
Key Trial Info
Start Date :
May 2 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 15 2018
Estimated Enrollment :
176 Patients enrolled
Trial Details
Trial ID
NCT03800264
Start Date
May 2 2018
End Date
November 15 2018
Last Update
January 15 2019
Active Locations (1)
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1
Ramymahrose
Cairo, Egypt, 02