Status:
COMPLETED
Recovery, Fatigability, and Proteomic Response to Aerobic Exercise Training in Healthy Individuals
Lead Sponsor:
George Mason University
Conditions:
Adult
Fatigue
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The purpose of this protocol is to investigate the role of expired non-metabolic carbon dioxide in the relationship between fatigability and recovery and the response to aerobic exercise training in h...
Detailed Description
Subjects will be recruited from the greater Washington D.C. metro area by word of mouth, university classes, healthcare provider referral, social media posting, and by posted fliers. Healthy males and...
Eligibility Criteria
Inclusion
- age 18-60
- body mass index \> 19 to \<35 kg/m2
- able to pedal leg cycle ergometer
- able to comprehend and speak English
Exclusion
- diabetes mellitus
- significant pulmonary dysfunction (eg. chronic obstructive lung disease; interstitial lung disease)
- hypertension
- anemia
- stroke
- cancer (other than melanoma)
- cardiac, pulmonary, thyroid, autoimmune, musculoskeletal, neurological, metabolic bone, mitochondrial, hepatic, renal, and/or psychiatric disease
- abnormal blood lipids
- active substance abuse or cognitive impairment
- chronic infection requiring antiviral or antibiotic treatment
- taking any medications that may limit exercise capacity or the ability to adapt to aerobic exercise training
- previously or currently on anticoagulant therapy or therapeutic hormone replacement/supplementation (excluding birth control)
- pregnant
- smoking
Key Trial Info
Start Date :
January 22 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 24 2019
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT03800342
Start Date
January 22 2019
End Date
April 24 2019
Last Update
May 16 2019
Active Locations (1)
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1
George Mason University
Fairfax, Virginia, United States, 22030