Status:
COMPLETED
Influence of Inflammation on Micronutrient Status Assessment
Lead Sponsor:
International Centre for Diarrhoeal Disease Research, Bangladesh
Collaborating Sponsors:
Newcastle University, UK
Conditions:
Healthy Infants
Eligibility:
All Genders
9-18 years
Phase:
NA
Brief Summary
Inflammation can influence several biochemical measurements those commonly used to interpret micronutrient status in children. Our primary objective is to investigate the effects of inflammation on se...
Detailed Description
Background: Subclinical micronutrient deficiencies remain a hidden aspect of malnutrition for which comprehensive data are lacking. Defining subclinical micronutrient deficiencies requires considerin...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- 9 - 18 months of age
- Infants with normal body temperature and normal CRP (\<5 mg/L)
- Infants receive breast milk from the mother at least once per day
- Mothers produce a breast milk containing 30-40 nmol vitamin A /g milk fat
- Infants received a high-dose vitamin A capsules at the time of the most recent national distribution campaign (within the last 2-4 months)
- Mother is 18 - 45 years of age
- Mother and her infant plan to stay in the study area for the duration of the study
- Exclusion criteria:
- Mother or infant has chronic disease
- Mother or infant has acute illness on the day of data collection
- Infant is anemic (Hb \<90 g/L)
- Infant has weight for length \<80% of the reference median
- Infants do not develop inflammation (CRP ≥5 mg/L) after PENTA vaccination
Exclusion
Key Trial Info
Start Date :
June 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2019
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT03801161
Start Date
June 1 2018
End Date
June 30 2019
Last Update
August 26 2019
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Clinical Trail Unit (CTU), icddr,b.
Dhaka, Bangladesh, 1212
2
Shaikh M Ahmad
Dhaka, Bangladesh, 1212