Status:

UNKNOWN

Surgical Protocol for Peri-implantitis Treatment

Lead Sponsor:

Università Vita-Salute San Raffaele

Conditions:

Peri-implantitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Peri-implant diseases are common post-restorative complications in implant rehabilitations and they occur with an incidence of 12-43%. Based on the available data in literature, the surgical therapy ...

Detailed Description

Peri-implantitis are defined as inflammatory diseases caused by bacterial biofilm around implant surface characterized by bleeding on probing, probing depth and eventually bone loss; if not successful...

Eligibility Criteria

Inclusion

  • presence of at least one screw-type titanium implant exhibiting bleeding and/or suppuration on probing combined with:
  • PPD ≥ 5 mm and bone loss ≥ 2 mm (compared to crestal bone levels at the time of placement of the reconstruction)
  • PPD ≥6 and bone loss ≥3 (not compared to crestal bone levels at the time of placement of the reconstruction)
  • single tooth and bridgework restorations without overhangs
  • no evidence of occlusal overload (i.e. occlusal contacts revealed appropriate adjustment),
  • treated chronic periodontitis and proper periodontal maintenance care
  • FMPS \< 20%
  • non-smoker or light smoking status in smokers (\<10 cigarettes per day)
  • implant function time ≥ 1 year.

Exclusion

  • Patients with uncontrolled diabetes
  • patients with osteoporosis or under bisphosphonate medication,
  • pregnant or lactating women
  • patients with a history of radiotherapy to the head and neck region
  • hollow implants
  • implant mobility
  • implants at which no position could be identified where proper probing measurements could be performed;
  • previous surgical treatment of the peri-implantitis lesions

Key Trial Info

Start Date :

July 2 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT03801187

Start Date

July 2 2018

End Date

December 31 2021

Last Update

November 3 2020

Active Locations (1)

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Università Vita-Salute San Raffaele

Milan, Italy, 20100