Status:

UNKNOWN

Effects of Different Exercise Training Modalities in Alpha-1 Antitrypsin Deficiency Patients

Lead Sponsor:

Schön Klinik Berchtesgadener Land

Conditions:

Chronic Obstructive Pulmonary Disease

Alpha 1-Antitrypsin Deficiency

Eligibility:

All Genders

40-80 years

Phase:

NA

Brief Summary

Pulmonary rehabilitation (PR) including exercise training is highly effective by improving health-related quality of life, exercise capacity and symptoms in patients with chronic obstructive pulmonary...

Eligibility Criteria

Inclusion

  • COPD patients with A1ATD (genotype PiZZ)
  • COPD patients without A1ATD (genotype PiMM)
  • Global initiative for chronic obstructive lung disease (GOLD) stage III-IV
  • Medical Treatment according to recent A1ATD guidelines

Exclusion

  • General exclusion criteria for physical Training such as acute coronary Syndrome, acute myo- or pericarditis, acute lung embolism, acute heart failure, orthopedic comorbidities which prevent patients from participating in exercise Training program.
  • No written informed consent
  • Non-compliance

Key Trial Info

Start Date :

January 10 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03802357

Start Date

January 10 2019

End Date

December 31 2021

Last Update

January 16 2019

Active Locations (1)

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Schoen Klinik Berchtesgadener Land

Schönau am Königssee, Germany, 83471