Status:
COMPLETED
Effects of Combined Physical-cognitive Training on Cognitive Function in MCI
Lead Sponsor:
Chiang Mai University
Conditions:
Mild Cognitive Impairment
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
The present study aims to investigate the effects of combined physical-cognitive training on cognitive function as well as peripheral BDNF level and mitochondrial function of individuals with MCI. It ...
Detailed Description
Recent research suggests that the benefits of combined physical-cognitive training may be greater than either physical or cognitive training alone. Nevertheless, this synergistic effect has been demon...
Eligibility Criteria
Inclusion
- meet criteria for mNCD (mild neurocognitive disorders), previously known as MCI, based on the recent DSM-V (Diagnostic Statistical Manual-V) criteria
- comprehend instructions and willing to participate
- able to comply with the study schedule and procedures
- not taking any medications for their cognition and not planning to start medications during the study trial
Exclusion
- presence of medical conditions that would be unsafe to exercise
- diagnosed with other neurological conditions (e.g. Parkinson's disease, Stroke, Multiple Sclerosis, AD) that affect cognition and mobility
- presence of depressive symptoms
- presence of acute or/and chronic disease that could not be controlled (e.g. Arthritis, Asthma, Hypertension, Diabetes mellitus, Coronary artery disease)
- exercise regularly (at least 30 min/day, 3 days/week)
Key Trial Info
Start Date :
March 18 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 28 2021
Estimated Enrollment :
128 Patients enrolled
Trial Details
Trial ID
NCT03805620
Start Date
March 18 2019
End Date
June 28 2021
Last Update
May 29 2024
Active Locations (1)
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1
Faculty of Associated Medical Sciences, Chiang Mai University
Chiang Mai, Thailand, 50200