Status:
COMPLETED
Delayed Sleep Timing in Teens Study
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Delayed Sleep Phase
Eligibility:
All Genders
16-19 years
Phase:
NA
Brief Summary
This study will (1) comprehensively characterize the substance use disorder (SUD) risk profile associated with adolescent Delayed Sleep Phase (DSP), and (2) probe whether SUD risk is diminished by alt...
Detailed Description
Mounting evidence indicates that delayed sleep phase (DSP) may confer risk for adolescent substance use (SU) and SUDs. However, the exact nature of this link and the mechanisms underlying it remain un...
Eligibility Criteria
Inclusion
- Age 16-19 years
- Currently in 11th or 12th grade and enrolled in a traditional high-school; or cyber school with synchronous classes (not home-schooled)
- Physically and psychiatrically healthy, as determined by instruments described below
- Provision of written informed consent and assent
- Additional inclusion criterion for Experimental protocol
- Meets operational definition of delayed sleep phase (DSP; weekend bedtime ≥1 AM)
Exclusion
- Significant or unstable acute or chronic medical conditions
- Past or current bipolar disorder or psychotic disorder
- Past or current substance use disorder other than alcohol use disorder or cannabis use disorder
- Past month recreational drug use other than alcohol, cannabis, and nicotine
- Current syndromal sleep disorders other than insomnia and delayed sleep phase disorder
- Medications that interfere with sleep and/or reward function (antidepressants, and stimulants prescribed for ADHD are permitted)
- Conditions that would interfere with the MRI procedures (e.g., non-removal ferromagnetic devices)
Key Trial Info
Start Date :
December 3 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2024
Estimated Enrollment :
142 Patients enrolled
Trial Details
Trial ID
NCT03806296
Start Date
December 3 2018
End Date
November 30 2024
Last Update
August 26 2025
Active Locations (1)
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1
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, United States, 15213