Status:
COMPLETED
Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia
Lead Sponsor:
All India Institute of Medical Sciences, Bhubaneswar
Conditions:
Treatment Resistant Schizophrenia
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
The proposed study will be conducted to compare the efficacy of maintenance ECT (M-ECT) vs Clozapine in treatment resistant schizophrenia (TRS) in terms of change in psychopathology measures and cereb...
Detailed Description
The proposed study is a prospective, randomized clinical trial in patients suffering from treatment-resistant schizophrenia (TRS) and will be conducted in the Department of Psychiatry, AIIMS, Bhubanes...
Eligibility Criteria
Inclusion
- Patients clinically diagnosed with treatment-resistant schizophrenia (TRS) (TRRIP consensus criteria).
- Patients aged 18-60 years of either sex.
- Patients giving voluntary written consent for participation in the study
Exclusion
- Patient already on Clozapine or ECT.
- History of psychoactive substance abuse or dependence.
- Co-morbid psychiatric, major medical, or neurological disorders.
- History of organicity or significant head injury.
- Pacemaker or metal in any part of the body excluding the mouth.
- Pregnant and breastfeeding females.
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03807882
Start Date
February 1 2019
End Date
June 30 2020
Last Update
June 16 2021
Active Locations (1)
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1
Dept of Psychiatry, Aiims, Bhubaneswar
Bhubaneswar, Odisha, India, 751019