Status:

ACTIVE_NOT_RECRUITING

The Effect of Deep Versus Moderate Muscle Relaxants in Men During and After Robotic Surgery for Prostate Cancer

Lead Sponsor:

Memorial Sloan Kettering Cancer Center

Conditions:

Prostate Cancer

Eligibility:

MALE

18-80 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to determine if there is a difference in intra-abdominal pressure which surgeons use during surgery and post-surgery pain in men who undergo robotic prostate surgery with ...

Eligibility Criteria

Inclusion

  • Adult patients under the age of 80
  • American Society of Anesthesiologists Physical Status 1, 2, 3.
  • Elective Robotic Prostatectomy
  • Patient undergoing surgery at Josie Robertson Surgical Center

Exclusion

  • Age younger than 18
  • Inability to provide informed consent
  • Allergy to rocuronium, sugammadex, midazolam, propofol, fentanyl, lidocaine, mannitol (IV Acetaeminophen), IV Acetaminophen, Ketorolac, Morphine, Hydromorphone, Dexamethasone, Zofran, Benadryl, Compazine
  • Neuromuscular disease
  • Any patient with previous abdominal surgery less than or equal to 20 years prior to scheduled surgery date
  • Patients with BMI\>35
  • Severe renal impairment (Creatinine clearance \< 30 ml/min)
  • Patient receiving Toremifene or any history of receiving Toremifene
  • Chronic pain patients
  • Patients receiving suboxone
  • Patients receiving succinylcholine

Key Trial Info

Start Date :

January 14 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2026

Estimated Enrollment :

139 Patients enrolled

Trial Details

Trial ID

NCT03808077

Start Date

January 14 2019

End Date

January 1 2026

Last Update

June 19 2025

Active Locations (1)

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Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065