Status:
COMPLETED
Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.
Lead Sponsor:
Aga Khan University
Conditions:
Postoperative Analgesia
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, co...
Detailed Description
After obtaining approval from Ethical Review Committee (ERC) of Aga Khan University Hospital Karachi (AKUH), and inform about the study to primary surgeon, informed written consent will be obtained fr...
Eligibility Criteria
Inclusion
- ASA I to III.
- Age \>18 years.
- Either sex.
- Elective Video assisted thoracotomy surgery (VATS) under general anaesthesia
Exclusion
- ASA IV \& V.
- Coagulation disorders.
- Infection at the vicinity of the surgical wound.
- Raised intracranial pressure.
- History of hypersensitivity or known allergy to any study drug.
- History of opioid addiction.
- History of seizure disorder.
- Those who are not willing to participate in the study.
- Allergy to local anesthetics.
- Duration of surgery greater than 2 hours.
Key Trial Info
Start Date :
June 25 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2023
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT03809442
Start Date
June 25 2019
End Date
August 31 2023
Last Update
July 31 2024
Active Locations (1)
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1
Aga Khan University Hospital
Karachi, Sindh, Pakistan, 74800