Status:
TERMINATED
Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy
Lead Sponsor:
Oregon Health and Science University
Conditions:
Maternal Psychological Distress
Postpartum Depression
Eligibility:
FEMALE
21-45 years
Phase:
NA
Brief Summary
The study is a pilot randomized control trial of a validated intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, developed to reduce risk for postpartum depression. This st...
Detailed Description
The study will involve an online screen of potentially eligible pregnant women. If participants are eligible after the online screen, they will be invited in for an in person assessment, including cog...
Eligibility Criteria
Inclusion
- Inclusion:
- female who is currently pregnant (8-22 weeks gestational age (GA) at time of screen)
- 21-45 years old
- single gestation
- fluently speak English
- be available and physically able to attend scheduled group meetings
- have a prior history of at least 1 major depressive episode (as determined through psychiatric interviewing).
- Exclusion (at enrollment):
- Magnetic Resonance Imaging (MRI) contraindication (e.g., metal in their body)
- major neurological or medical illness (e.g., diabetes, multiple sclerosis)
- history of head trauma (loss of conscious \> 2 minutes)
- Intelligence Quotient (IQ) \< 80
- uncorrectable vision or hearing impairments (including color blindness)
- use of psychotropic medications, corticosteroids, insulin, or any other medications that might impact the central nervous system
- current illicit drug use or diagnosis of a current substance use disorder
- current diagnosis of an eating disorder
- current depressive or manic episode
- diagnosis of a neurodevelopmental disorder (Autism, Intellectual Disability)
- any history of psychosis
- current active suicidality and/or homicidality, or interpersonal violence
- prior history of engaging in mindfulness-based psychotherapeutic interventions (e.g., Mindfulness Based Cognitive Therapy (MBCT), Mindfulness Based Stress Reduction (MBSR), Dialectical Behavior Therapy (DBT))
- known congenital, genetic, or neurologic disorder of the fetus (e.g., Down syndrome, fragile X)
- pregnancy-specific medical conditions or complications that significantly increase risk (e.g., placental separation, placenta previa)
- History of meningitis or seizures (except infantile or febrile)
Exclusion
Key Trial Info
Start Date :
March 22 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 8 2021
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT03809572
Start Date
March 22 2019
End Date
March 8 2021
Last Update
December 20 2021
Active Locations (1)
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1
Oregon Health and Science University
Portland, Oregon, United States, 97239